in vitroScientific Research: IN VITRO AND RELATED STUDIES

Read about more about scientific research on homeopathy

Phenotypic evidence of ultra-highly diluted homeopathic remedies acting at gene expression level: a novel probe on experimental phage infectivity in bacteria. Saha SK, Das S, Khuda-Bukhsh AR. Source Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani 741235, India; E-mail: prof_arkb@yahoo.co.in, khudabukhsh_48@rediffmail.com. Zhong Xi Yi Jie He Xue Bao. 2012 Apr;10(4):462-70.

Effects of two homeopathic complexes on bovine sperm mitochondrial activity. Aziz DM, Schnurrbusch U, Enbergs H. Source Institute of Physiology, Biochemistry and Hygiene of Animals, Bonn University, Bonn, Germany. Homeopathy. 2012 Apr;101(2):99-102.

Effects of Calendula officinalis on human gingival fibroblasts. Saini P, Al-Shibani N, Sun J, Zhang W, Song F, Gregson KS, Windsor LJ. Source Department of Periodontics, Indiana University School of Dentistry, 1121 West Michigan Street, DS 423, Indianapolis, IN 46202, USA. Homeopathy. 2012 Apr;101(2):92-8.

Therapeutic Effect of Arsenicum album on Leukocytes. Elaine C. Ive,1 Ingrid M. S. Couchman,1 and Lalini Reddy2* 1Department of Homoeopathy, Faculty of Health Sciences, Durban University of Technology, P.O. Box 1334, Durban 4000, South Africa; E-Mails: elaine.ive0@gmail.com (E.C.I.); Email: ingridc@dut.ac.za (I.M.S.C.)2Department of Biotechnology and Food Technology, Faculty of Applied Sciences, Durban University of Technology, P.O. Box 1334, Durban 4000, South Africa. Int J Mol Sci. 2012; 13(3): 3979–3987. Published online 2012 March 22. doi: 10.3390/ijms13033979 PMCID: PMC3317753 Copyright © 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.

Potentized homeopathic drug Arsenicum Album 30C inhibits intracellular reactive oxygen species generation and up-regulates expression of arsenic resistance gene in arsenine-exposed bacteria Escherichia coli. De A, Das D, Dutta S, Chakraborty D, Boujedaini N, Khuda-Bukhsh AR. Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani 741235, India; E-mail: prof_arkb@yahoo.co.in, khudabukhsh_48@rediffmail.com. Zhong Xi Yi Jie He Xue Bao. 2012 Feb;10(2):210-27.

Lymphocyte proliferation stimulated by activated Cebus apella macrophages treated with a complex homeopathic immune response modifiers. Coelho Moreira CO, de Fátima Ferreira Borges da Costa J, Leal MF, Ferreira de Andrade E, Rezende AP, Imbeloni AA, Pereira Carneiro Muniz JA, de Arruda Cardoso Smith M, Burbano RR, de Assumpção PP. Laboratório de Citogenética Humana, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, PA, Brazil; Serviço de Cirurgia, Hospital Universitário João de Barros Barreto, Universidade Federal do Pará, Belém, PA 66073-000, Brazil. Homeopathy. 2012 Jan;101(1):74-9.

Nonlinear changes in the activity of the oxygen-dependent demethylase system in Rhodococcus erythropolis cells in the presence of low and very low doses of formaldehyde. Malarczyk E, Pazdzioch-Czochra M, Grąz M, Kochmańska-Rdest J, Jarosz-Wilkołazka A. Biochemistry Department, UMCS, Lublin, Poland. malar@poczta.umcs.lublin.pl. Nonlinear Biomed Phys. 2011 Nov 21;5(1):9.

Developments on drug discovery and on new therapeutics: highly diluted tinctures act as biological response modifiers. Carolina C de Oliveira , Ana Paula R Abud , Simone M de Oliveira , Fernando DE SF Guimaraes , Lucas F de Andrade , Raffaello P di Bernardi , Ediely L DE O Coletto , Diogo Kuczera , Eneida J da Lozzo , Jenifer P Goncalves , Edvaldo DA S Trindade and Dorly DE F Buchi. Laboratório de Estudos de Células Inflamatórias e Neoplásicas, Departamento de Biologia Celular, SCB, Centro Politecnico, Universidade Federal do Paraná – Curitiba, PR – Brazil CEP 81531-980. BMC Complementary and Alternative Medicine 2011, 26 October 2011. 11:101doi:10.1186/1472-6882-11-101

Ultra High Dilution of triiodothyronine modifies cellular apoptosis in Rana catesbeiana tadpole tail in vitro. Guedes JR, Carrasco S, Ferreira CM, Bonamin LV, Souza W, Goldenstein-Schainberg C, Parra ER, Capelozzi VL. Laboratory of Molecular Pathology, Department of Pathology, University of São Paulo School of Medicine, SP, Brazil. Homeopathy. 2011 Oct;100(4):220-7.

Mercurius solubilis: actions on macrophages. de Oliveira SM, de Oliveira CC, Abud AP, Guimarães Fde S, Di Bernardi RP, Coletto EL, Buchi Dde F. Laboratório de Estudos de Células Inflamatórias e Neoplásicas, Departamento de Biologia Celular, SCB, Universidade Federal do Paraná, Curitiba, PR, Brazil. Homeopathy. 2011 Oct;100(4):228-36.

Toxicology rewrites its history and rethinks its future: Giving equal focus to both harmful and beneficial effects. Calabrese EJ. School of Public Health and Health Sciences, Department of Public Health; Environmental Health Sciences, University of Massachusetts; Amherst, Massachusetts, USA. Environ Toxicol Chem. 2011 Sep 19. doi: 10.1002/etc.687.

Potentized homeopathic drug Arsenicum Album 30C positively modulates protein biomarkers and gene expressions in Saccharomyces cerevisae exposed to arsenate. Das D, De A, Dutta S, Biswas R, Boujedaini N, Khuda-Bukhsh AR. Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani 741235, India; E-mail: prof_arkb@yahoo.co.in, khudabukhsh_48@rediffmail.com. Zhong Xi Yi Jie He Xue Bao. 2011 Jul;9(7):752-60.

Effects of 200cH medications on mice bone marrow cells and macrophages. Carolina de Oliveira, Ana Paula R. Abud, Eneida Da Lozzo, Raffaello Di Bernardi, Simone de Oliveira, Fernando de SF. Guimarães, Dorly de F. Buchi. International Journal of High Dilution Research, Vol 10, No 35 (2011)

Thujone-Rich Fraction of Thuja occidentalis Demonstrates Major Anti-Cancer Potentials: Evidences from In Vitro Studies on A375 Cells. Biswas R, Mandal SK, Dutta S, Bhattacharyya SS, Boujedaini N, Khuda-Bukhsh AR. Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani 741235, India. Evid Based Complement Alternat Med. 2011;2011:568148. Epub 2011 Feb 20.

Inhibition of peripheral blood neutrophil oxidative burst in periodontitis patients with a homeopathic medication Traumeel. S. Zilinskas J, Zekonis J, Zekonis G, Sadzevičienė R, Sapragonienė M, Navickaitė J, Barzdžiukaitė I. Med Sci Monit. 2011 May 2;17(5):CR284-291. STOMATOLOGIJA Baltic Dental and Maxillofacial Journal, Kaunas, Lithuania.

Homeopathic medications help fight viral infections. This has now been confirmed by in-vitro tests conducted at the Dr. Glatthaar Laboratory in Reutlingen, Germany. Researchers infected epithelial and blood cells with cold viruses under controlled laboratory conditions. March 15, 2011

Antiviral Action of a Homeopathic Medication. Horst Metelman, Bernadette Glatthar Saalmuller Biologische Medizin 1999 June: 42 – 146

In vitro evaluation of the antiviral effects of the homeopathic preparation Gripp-Heel on selected respiratory viruses. Glatthaar-Saalmüller B. Can J Physiol Pharmacol. 2007 Nov;85(11):1084-90.

Antiviral activity of Engystol: an in vitro analysis. Oberbaum M, Glatthaar-Saalmüller B, Stolt P, Weiser M. J Altern Complement Med. 2005 Oct;11(5):855-62. Erratum in: J Altern Complement Med. 2005 Dec;11(6):1122.

[Influence of homeopathically processed coenzyme q10 on proliferation and redifferentiation of endothelial cells].Glatthaar-Saalmüller B, Fallier-Becker P, Weiser M.Forsch Komplementarmed Klass Naturheilkd. 2004 Oct;11(5):267-73. German.

Antiviral action of Euphorbium compositum and its components. Glatthaar-Saalmüller B, Fallier-Becker P. Forsch Komplementarmed Klass Naturheilkd. 2001 Aug;8(4):207-12.

Effects of the utilization of homeopathic elements in commercial diluent on swine sperm viability. Soto FR, Vuaden ER, de Paula Coelho C, Bonamin LV, de Azevedo SS, Benites NR, de Barros FR, Goissis MD, Ortiz D’Ávila Assumpção ME, Visintin JA, Marques MG. Center for Sanitary Surveillance and Zoonoses Control “Tereza Rodrigues de Camargo”, Estrada da Vargem do Salto- Km 4,5- Bairro dos Paes, 18150-000, Ibiúna, São Paulo, Brazil. In Vitro Cell Dev Biol Anim. 2011 Feb 27.

In Vitro and In Vivo Studies Demonstrate Anticancer Property of Root Extract of Polygala Senega. Paul S, Mandal SK, Bhattacharyya SS, Boujedaini N, Khuda-Bukhsh AR. Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani, India. J Acupunct Meridian Stud. 2010 Sep;3(3):188-196.

Heparin-binding epidermal growth factor expression in KATO-III cells after Helicobacter pylori stimulation under the influence of strychnos Nux vomica and Calendula officinalis. Hofbauer R, Pasching E, Moser D, Frass M. Medical University of Vienna, Department of Medicine I, Division of Oncology, Austria. Homeopathy. 2010 Jul;99(3):177-182.

Efficacy of homeopathically potentized antimony on blood coagulation. A randomized placebo controlled crossover trial. Heusser P, Berger S, Stutz M, Hüsler A, Haeberli A, Wolf U. Department of Anthroposophic Medicine, Institute of Complementary Medicine KIKOM, University of Bern, Switzerland. Forsch Komplementmed. 2009 Feb;16(1):14-8.

Encapsulated plant extract (Gelsemium sempervirens) poly (lactide-co-glycolide) nanoparticles enhance cellular uptake and increase bioactivity in vitro. Bhattacharyya SS, Paul S, Khuda-Bukhsh AR. Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani-741235, West Bengal, India. Exp Biol Med (Maywood). 2010 Jun 1;235(6):678-88.

Inhibition of CD203c membrane up-regulation in human basophils by high dilutions of histamine: a controlled replication study. Salvatore Chirumbolo,1 Maurizio Brizzi, 2 Riccardo Ortolani, 3 Antonio Vella, 3 and Paolo Bellavite, 1 1Department of Morphological and Biomedical Science, University of Verona, Piazza L.A: Scuro, 10, 37134 Verona, Italy, 2 P. Fortunati Institute of Statistics, University of Bologna, Bologna, Italy, 3 Department of Pathology-Immunology Section, University of Verona, Verona, Italy. Inflamm Res. 2009 November; 58(11): 755–764. Published online 2009 May 6.

Influence of very low doses of mediators on fungal laccase activity – nonlinearity beyond imagination. Malarczyk E, Kochmanska-Rdest J, Jarosz-Wilkolazka A. Biochemistry Department, Maria Curie-Skłodowska University, Lublin, Poland. Nonlinear Biomed Phys. 2009 Sep 4;3(1):10. Read the whole report here.

Treatment with at Homeopathic Complex Medication Modulates Mononuclear Bone Marrow Cell Differentiation. Cesar B, Abud AP, de Oliveira CC, Cardoso F, Bernardi RP, Guimarães FS, Gabardo J, de Freitas Buchi D. UFPR, Centro Politécnico, SCB, Depto de Biologia Celular, sala 215, Laboratório de Estudo de Células Inflamatórias e Neoplásicas, Jardim das Américas, Curitiba, CEP 81531-980, PR, Brazil.  Evid Based Complement Alternat Med. 2009 Sep 7

Immunomodulatory activity of Toxicodendron pubescens in experimental models. Patil CR, Salunkhe PS, Gaushal MH, Gadekar AR, Agrawal AM, Surana SJ. R.C. Patel Institute of Pharmaceutical Education and Research, Near Karwand Naka, Shirpur-425405, District Dhule, Maharashtra, India. Homeopathy. 2009 Jul;98(3):154-9

Electromagnetic Signals Are Produced by Aqueous NanostructuresDerived from Bacterial DNA Sequence. Luc Montagnier, Jamal Aissa, Stéphane Ferris, Jean-Luc Montagnier, Claude Lavallee, Interdiscip Sci Comput Life Sci (2009) 1: 81-90

Lymphocyte proliferation stimulated by activated human macrophages treated with Canova. Burbano RR, Leal MF, da Costa JB, Bahia Mde O, de Lima PD, Khayat AS, Seligman IC, de Assumpção PP, Buchi Dde F, Smith Mde A. Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, PA, Brazil. Homeopathy. 2009 Jan;98(1):45-8.

In Vitro Studies Demonstrate Anticancer Activity of an Alkaloid of the Plant Gelsemium sempervirens. Bhattacharyya SS, Mandal SK, Biswas R, Paul S, Pathak S, Boujedaini N, Belon P, Khuda-Bukhsh AR. Department of Zoology, University of Kalyani, Kalyani-741235, India. Exp Biol Med (Maywood). 2008 Dec;233(12):1591-601. Epub 2008 Nov 7.

Differentiation of human monocytes in vitro following exposure to Canova in the absence of cytokines. Smit E, Pretorius E, Anderson R, Oommen J, Potjo M. Department of Anatomy, School of Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa. Ultrastruct Pathol. 2008 Jul-Aug;32(4):147-52

In vitro evaluation of the antiviral effects of the homeopathic preparation Gripp-Heel on selected respiratory viruses Glatthaar-Saalmüller B. Labor Dr. Glatthaar, Clinical Immunology, University of Veterinary Medicine Vienna, A-1210 Vienna, Austria (e-mail: glatthaar@l-d-g.de). Can J Physiol Pharmacol. 2007 Nov;85(11):1084-90

Does potentized HgCl2 (Mercurius c orrosivus) affect the activity of diastase and alpha-amylase? Witt CM, Bluth M, Hinderlich S, Albrecht H, Lüdtke R, Weisshuhn TE, Willich SN. Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, Berlin, Germany. claudia.witt@charite.de J Altern Complement Med. 2006 May;12(4):359-65

Histamine dilutions modulate basophil activation Belon P, Cumps J, Ennis M, Mannaioni PF, Roberfroid M, Sainte-Laudy J, Wiegant FA. Boiron, 20 rue de la Libération, 69110 Sainte-Foy-Les-Lyon, France Inflamm Res. 2004 May;53(5):181-8. Epub 2004 Apr 21

In-Vitro Activity of Thuja Occidentalis Linn. Against Pathogenic Aspergilli Dr. Girish Gupta Dr. A. K. Srivastava The Homoeopathic Heritage Vol. 27, No. 1, January 2002 pg. 5 – 12.

The in vitro evidence for an effect of high homeopathic potencies–a systematic review of the literature Witt CM, Bluth M, Albrecht H, Weisshuhn TE, Baumgartner S, Willich SN. Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, D-10098 Berlin, Germany. claudia.witt@charite.de Complement Ther Med. 2007 Jun;15(2):128-38. Epub 2007 Mar 28

Biochemical efficacy of homeopathic and electronic preparations of D8 potassium cyanate Dittmann J, Kanapin H, Harisch G.Institut für Physiologische Chemie, Tierärztliche Hochschule Hannover, Deutschland Forsch Komplementarmed. 1999 Feb;6(1):15-8

Effect of low doses and high homeopathic potencies in normal and cancerous human lymphocytes: an in vitro isopathic study Wälchli C, Baumgartner S, Bastide M. Institute for Complementary Medicine (KIKOM), University of Bern, Bern, Switzerland. waelchli@hiscia.ch J Altern Complement Med. 2006 Jun;12(5):421-7

Activation of mononuclear bone marrow cells treated in vitro with a complex homeopathic medication Cesar B, Abud AP, de Oliveira CC, Cardoso F, Gremski W, Gabardo J, Buchi DD. Departamento de Biologia Celular, Setor de Ciências Biológicas, Universidade Federal do Paraná (UFPR), Curitiba, PR, Brazil Micron. 2007 Feb 22; [Epub ahead of print]

In vivo treatment of melanoma (B16F10) with a homeopathic agent and with a cytokine (IFN-alpha) Pascual-Carpe F, Vicente-Ortega V, Campos-Aranda M, Yañez-Gascón J. Department of Pathology, Faculty of Medicine, Murcia University, Espinardo Campus,30100 Murcia, Spain Oncol Res. 2006;16(5):211-6

Investigation of cytokine expression in human leukocyte cultures with two immune-modulatory homeopathic preparations Ramachandran C, Nair PK, Clèment RT, Melnick SJ. Research Institute, Miami Children’s Hospital, Miami, Florida 33155, USA. cheppail.ramachandran@mch.com J Altern Complement Med. 2007 May;13(4):403-7

In vivo study of the anti-inflammatory effect of Rhus toxicodendron dos Santos AL, Perazzo FF, Cardoso LG, Carvalho JC. Faculdade de Ciências da Saúde de São Paulo, R. Bartolomeu de Gusmão, São Paulo, São Paulo, Brazil Homeopathy. 2007 Apr;96(2):95-101

Antioxidative, antiproliferative and biochemical effects in HepG2 cells of a homeopathic remedy and its constituent plant tinctures tested separately or in combination Gebhardt R. Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany. rgebhardt@medizin.uni-leipzig.de Arzneimittelforschung. 2003;53(12):823-30

Comparative analysis of the influence of various factors in different combinations on the ionic homeostasis of a cell NadareÄ­shvili GG. Georgian Med News. 2006 Aug;(137):109-11

Influence of some homeopathic preparations on tumor cells NadareÄ­shvili GG. Georgian Med News. 2006 Jul;(136):99-101

Influences of some homeopathic preparations on ionic homeostasis at different dilutions NadareÄ­shvili GG. Georgian Med News. 2006 Jun;(135):120-3

Dual inhibition of 5-lipoxygenase/cyclooxygenase by a reconstituted homeopathic remedy; possible explanation for clinical efficacy and favourable gastrointestinal tolerability Jäggi R, Würgler U, Grandjean F, Weiser M. VitaPlant AG, Benkenstrasse 254, 4108 Witterswil, Switzerland. rjaeggi@vitaplant.ch Inflamm Res. 2004 Apr;53(4):150-7. Epub 2004 Mar 18

Inhibition of IL-1beta and TNF-alpha secretion from resting and activated human immunocytes by the homeopathic medication Traumeel S Porozov S, Cahalon L, Weiser M, Branski D, Lider O, Oberbaum M. The Center for Integrative Complementary Medicine, Shaare Zedek Medical Center, Jerusalem 91031, Israel Clin Dev Immunol. 2004 Jun;11(2):143-9

Phagocytosis, endosomal/lysosomal system and other cellularaspects of macrophage activation by Canova medication Lopes L, Godoy LM, de Oliveira CC, Gabardo J, Schadeck RJ, de Freitas Buchi D Laboratório de Estudos de Células Inflamatórias e Neoplásicas, Departamento de Biologia Celular, Universidade Federal do Paraná, Brazil Micron. 2006;37(3):277-87. Epub 2005 Sep 19

Effects of the homeopathic preparation Engystol on interferon-gamma production by human T-lymphocytes Enbergs H. Institute of Physiology, Biochemistry and Animal Hygiene, University of Bonn, Germany. heinrich.enbergs@medscape.com Immunol Invest. 2006;35(1):19-27

A rapid TLC screening method for the quality control of Sedum acre L. homeopathic tinctures B Gehrmann1, MF Melzig2 1 Einhorn-Rats-Apotheke, Markt 10–12, 25813 Husum, Germany 2 Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195 Berlin, Germany

Antiviral activity of Engystol: an in vitro analysis Oberbaum M, Glatthaar-Saalmüller B, Stolt P, Weiser M. The Center of Integrated Complementary Medicine, Shaare Zedek Medical Center, Jerusalem, Israel. oberbaum@szmc.org.il J Altern Complement Med. 2005 Oct;11(5):855-62

Effects of ultrahigh dilutions of 3,5-dichlorophenol on the luminescence of the bacterium Vibrio fischeri Antje Brack, a, b, Jürgen Strubea, Peter Stolza and Heinz Deckerb a Forschungsinstitut Kwalis gGmbH, Fuldaer Str. 21, Dipperz 36160, Germany b Institute for Molecular Biophysics, Johannes Gutenberg University Mainz, Mainz, Germany Biochimica et Biophysica Acta (BBA) – General Subjects
Volume 1621, Issue 3, 11 June 2003, Pages 253-260

Histamine dilutions modulate basophil activation Belon P, Cumps J, Ennis M, Mannaioni PF, Roberfroid M, Sainte-Laudy J, Wiegant FA. Boiron, 20 rue de la Libération, 69110 Sainte-Foy-Les-Lyon, France Inflamm Res. 2004 May;53(5):181-8. Epub 2004 Apr 21

Effects of Saussurea lappa roots extract in ethanol on leukocyte phagocytic activity, lymphocyte proliferation and interferon-gamma (IFN-gamma) Sarwar A, Enbergs H. Department of Veterinary Anatomy, University of Agriculture 38040, Faisalabad, Pakistan. anas_sarwar@hotmail.com Pak J Pharm Sci. 2007 Jul;20(3):175-9